Partial RdRp sequences offer a robust method for Coronavirus subgenus classification

David A Wilkinson; Lea Joffrin; Camille Lebarbenchon; Patrick Mavingui

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.02.974311 doi: bioRxiv preprint of the query sequence to the reference database. The predicted subgenus and genus of the best-433 matching hit are displayed, as well as the posterior support for the assignment to the predicted 434 subgenus (see methods). Pairwise identity between the two sequences is shown and is calculated 435 relative to the maximum possible alignment length against the reference sequences (387 bp). B) For 436 each queried sequence, pairwise identity values are mapped to all observations from pairwise 437 comparisons between sequences in the database. The vertical dashed line represents the pairwise 438 dissimilarity of the queried sequence. C) Phylogenetic positioning and metadata from the analysis of 439 the reference sequences are displayed. Reference sequences with blast-hits matching the queried 440 sequence are highlighted on the leaves, and tips are coloured from red to green with increasing 441 pairwise identity. The hit with the best score is highlighted by a large green diamond on the tip. 442