Selected article for: "immunosuppressive therapy and infection risk"

Author: Singh, Suvir; Singh, Jagdeep; Paul, Davinder; Jain, Kunal
Title: Treatment of Acute Leukemia during COVID-19: Focused review of evidence
  • Cord-id: md61rehn
  • Document date: 2021_1_12
  • ID: md61rehn
    Snippet: The COVID-19 pandemic is an unprecedented healthcare crisis, and has led to over 1.5 million deaths worldwide. The risk of severe COVID-19 and mortality is markedly raised in patients with cancer, prompting several collaborative groups to issue guidelines to mitigate the risk of infection by delaying or de-escalating immunosuppressive therapy. However, delayed therapy is often not feasible for patients requiring treatment for acute leukemia or stem cell transplantation. We provide a focused revi
    Document: The COVID-19 pandemic is an unprecedented healthcare crisis, and has led to over 1.5 million deaths worldwide. The risk of severe COVID-19 and mortality is markedly raised in patients with cancer, prompting several collaborative groups to issue guidelines to mitigate the risk of infection by delaying or de-escalating immunosuppressive therapy. However, delayed therapy is often not feasible for patients requiring treatment for acute leukemia or stem cell transplantation. We provide a focused review of the recommendations and evidence for managing this high risk group of patients while minimizing the risk of COVID19 infection, and provide a small snapshot of treatment data from our centre.

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