Author: Jingyue Ju; Shiv Kumar; Xiaoxu Li; Steffen Jockusch; James J. Russo
Title: Nucleotide Analogues as Inhibitors of Viral Polymerases Document date: 2020_1_31
ID: dpcpg5c1_3
Snippet: All RNA viruses are known to mutate at a high frequency, due to the low fidelity of the viral polymerase, resulting in the development of resistance to treatment. The promiscuous nature of the viral polymerase will allow incorporation of our newly designed nucleotide analogues as anti-viral agents......
Document: All RNA viruses are known to mutate at a high frequency, due to the low fidelity of the viral polymerase, resulting in the development of resistance to treatment. The promiscuous nature of the viral polymerase will allow incorporation of our newly designed nucleotide analogues as anti-viral agents.
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