Author: Arachchillage, Deepa J.; Stacey, Arthur; Akor, Frances; Scotz, Martin; Laffan, Mike
Title: Thrombolysis restores perfusion in COVIDâ€19 hypoxia Cord-id: w8nv0qf8 Document date: 2020_8_17
ID: w8nv0qf8
Snippet: Thrombolysis with tissue plasminogen activator (tPA) is an established treatment strategy for patients with intermediate and high-risk pulmonary embolism (PE) and signs of haemodynamic instability. The use of tPA in coronavirus disease -19 (COVID-19) patients with PE and acute respiratory distress syndrome (ARDS) may be of benefit due to the unusually high incidence of pulmonary embolism and pulmonary thrombosis, particularly microvascular thrombosis which are thought to contribute significantly
Document: Thrombolysis with tissue plasminogen activator (tPA) is an established treatment strategy for patients with intermediate and high-risk pulmonary embolism (PE) and signs of haemodynamic instability. The use of tPA in coronavirus disease -19 (COVID-19) patients with PE and acute respiratory distress syndrome (ARDS) may be of benefit due to the unusually high incidence of pulmonary embolism and pulmonary thrombosis, particularly microvascular thrombosis which are thought to contribute significantly to hypoxemia(1).
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