Selected article for: "different host and influenza virus"
Author: Danielle E Anderson; Jin Cui; Qian Ye; Baoying Huang; Wenhong Zu; Jing Gong; Weiqiang Liu; So Young Kim; Biao Guo Yan; Kristmundur Sigmundsson; Xiao Fang Lim; Fei Ye; Peihua Niu; Xuming Zhou; Wenjie Tan; Lin-Fa Wang; Xu Tan
Title: Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapy
  • Document date: 2020_3_30
    • ID: 0l33i6s4_6
    Snippet: for the whole genome of the model megabat Pteropus Alecto. We screened two viruses, influenza 20 A virus and mumps virus, using the CRISPR and RNAi libraries, respectively, in the hope of 21 uncovering common host factors for different viruses. From these two screens, common pathways 22 such as the endocytosis pathway and protein secretory pathway have been identified, 23 demonstrating conserved pathways between bat and other mammals in hosting v.....
    Document: for the whole genome of the model megabat Pteropus Alecto. We screened two viruses, influenza 20 A virus and mumps virus, using the CRISPR and RNAi libraries, respectively, in the hope of 21 uncovering common host factors for different viruses. From these two screens, common pathways 22 such as the endocytosis pathway and protein secretory pathway have been identified, 23 demonstrating conserved pathways between bat and other mammals in hosting viral infections. 24

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