Author: Yuri I. Wolf; Darius Kazlauskas; Jaime Iranzo; Adriana LucÍa-Sanz; Jens H. Kuhn; Mart Krupovic; Valerian V. Dolja; Eugene V. Koonin
Title: Origins and Evolution of the Global RNA Virome Document date: 2018_10_24
ID: 8z78shbf_29
Snippet: The previously suggested, tenuous Flaviviridae-Tombusviridae affinity is gone in the present 446 tree although members of both families belong to the same major Branch 3. Plant tombusviruses 447 (and members of closely related plant virus genera), the only group of "tombus-like viruses" that 448 was available at the time of previous analyses (7, 21), now form but a small twig deep within the 449 large assemblage we refer to as tombusviruses. Tomb.....
Document: The previously suggested, tenuous Flaviviridae-Tombusviridae affinity is gone in the present 446 tree although members of both families belong to the same major Branch 3. Plant tombusviruses 447 (and members of closely related plant virus genera), the only group of "tombus-like viruses" that 448 was available at the time of previous analyses (7, 21), now form but a small twig deep within the 449 large assemblage we refer to as tombusviruses. Tombusviruses are affiliated with "statoviruses" 450 (80) and a subset of unclassified viruses from invertebrate holobionts rather than with 451 flaviviruses ( Figure 4A) . Flaviviruses now form a separate clade within Branch 3, the flavivirus 452 supergroup that includes members of four recognized flaviviral genera (Pegivirus, Hepacivirus, 453
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