Author: Roni Ben-Ami; Agnes Klochendler; Matan Seidel; Tal Sido; Ori Gurel-Gurevich; Moran Yassour; Eran Meshorer; Gil Benedek; Irit Fogel; Esther Oiknine-Djian; Asaf Gertler; Zeev Rotstein; Bruno Lavi; Yuval Dor; Dana G Wolf; Maayan Salton; Yotam Drier
Title: Pooled RNA extraction and PCR assay for efficient SARS-CoV-2 detection Document date: 2020_4_22
ID: 5s03f0pp_27
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04. 17.20069062 doi: medRxiv preprint Future improvement of the sensitivity of the test, such as better sets of primers, improved sample collection and inclusion of information about pre-test probability will allow retaining sensitivity even when pooling a large number of sample lysates together. This will enable further improving efficiency.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04. 17.20069062 doi: medRxiv preprint Future improvement of the sensitivity of the test, such as better sets of primers, improved sample collection and inclusion of information about pre-test probability will allow retaining sensitivity even when pooling a large number of sample lysates together. This will enable further improving efficiency, especially when prevalence is low, by increasing the pool size.
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