Selected article for: "control cell and steady state"
Author: Choreño-Parra, José Alberto; Thirunavukkarasu, Shyamala; Zúñiga, Joaquín; Khader, Shabaana A.
Title: The protective and pathogenic roles of CXCL17 in human health and disease: Potential in respiratory medicine
  • Cord-id: mhhpta57
  • Document date: 2020_4_23
    • ID: mhhpta57
    Snippet: C-X-C motif chemokine 17 (CXCL-17) is a novel chemokine that plays a functional role maintaining homeostasis at distinct mucosal barriers, including regulation of myeloid-cell recruitment, angiogenesis, and control of microorganisms. Particularly, CXCL17 is produced along the epithelium of the airways both at steady state and under inflammatory conditions. While increased CXCL17 expression is associated with disease progression in pulmonary fibrosis, asthma, and lung/hepatic cancer, it is though
    Document: C-X-C motif chemokine 17 (CXCL-17) is a novel chemokine that plays a functional role maintaining homeostasis at distinct mucosal barriers, including regulation of myeloid-cell recruitment, angiogenesis, and control of microorganisms. Particularly, CXCL17 is produced along the epithelium of the airways both at steady state and under inflammatory conditions. While increased CXCL17 expression is associated with disease progression in pulmonary fibrosis, asthma, and lung/hepatic cancer, it is thought to play a protective role in pancreatic cancer, autoimmune encephalomyelitis and viral infections. Thus, there is emerging evidence pointing to both a harmful and protective role for CXCL17 in human health and disease, with therapeutic potential for translational applications. In this review, we provide an overview of the discovery, characteristics and functions of CXCL17 emphasizing its clinical potential in respiratory disorders.

    Search related documents:
    Co phrase search for related documents
    • absence presence and active process: 1, 2, 3
    • absence presence and activity responsible: 1, 2
    • absence presence and adaptive immunity: 1, 2, 3, 4
    • absence presence and adhesion molecule: 1, 2, 3, 4
    • absence presence and local level: 1, 2
    • absence presence and lung airway: 1
    • absence presence and lung cancer: 1, 2, 3, 4
    • absence presence and lung cancer cell: 1
    • absence presence and lung disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • absence presence and lung fibroblast: 1
    • absence presence and lung interstitial: 1, 2, 3
    • absence presence and lung macrophage: 1
    • absence presence and lung parenchyma: 1
    • absence presence and lung sample: 1
    • absence presence and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8
    • absence presence and lymph node: 1, 2, 3, 4, 5