Author: Gibson, Elena G; Pender, Melissa; Angerbauer, Michael; Cook, Craig; Jones, Barbara; Spivak, Adam M; Swaminathan, Sankar; Spivak, Emily S
Title: Prolonged SARS CoV-2 Illness in a Patient Receiving Ocrelizumab for Multiple Sclerosis Cord-id: mn62chw0 Document date: 2021_4_8
ID: mn62chw0
Snippet: We describe a case of prolonged SARS CoV-2 infection in a patient receiving ocrelizumab for multiple sclerosis. Viral RNA shedding, signs, and symptoms persisted for 69 days with resolution after administration of convalescent plasma and antiviral therapy. This case suggests risk for persistent SARS CoV-2 infection in patients treated with anti-CD-20 monoclonal antibodies and supports a role for humoral immunity in disease resolution.
Document: We describe a case of prolonged SARS CoV-2 infection in a patient receiving ocrelizumab for multiple sclerosis. Viral RNA shedding, signs, and symptoms persisted for 69 days with resolution after administration of convalescent plasma and antiviral therapy. This case suggests risk for persistent SARS CoV-2 infection in patients treated with anti-CD-20 monoclonal antibodies and supports a role for humoral immunity in disease resolution.
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