Author: Ashish Goyal; E. Fabian Cardozo-Ojeda; Joshua T Schiffer
Title: Potency and timing of antiviral therapy as determinants of duration of SARS CoV-2 shedding and intensity of inflammatory response Document date: 2020_4_14
ID: d7stppv5_36
Snippet: We generalized the potential effects of a cellular immunotherapy which would presumably decrease the lifespan of infected cells. We projected that such an intervention would need to increase this rate 10-fold to match the efficacy of a potent small molecular agent. (Fig. S7a-c) . Immunotherapies were projected to have no efficacy if started prior to peak shedding (Fig. S7d )......
Document: We generalized the potential effects of a cellular immunotherapy which would presumably decrease the lifespan of infected cells. We projected that such an intervention would need to increase this rate 10-fold to match the efficacy of a potent small molecular agent. (Fig. S7a-c) . Immunotherapies were projected to have no efficacy if started prior to peak shedding (Fig. S7d ).
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