Author: JIANLIN XIANG; JING WEN; XIAOQING YUAN; Shun Xiong; XUE ZHOU; CHANGJIN LIU; XUN MIN
Title: Potential biochemical markers to identify severe cases among COVID-19 patients Document date: 2020_3_23
ID: 6rs86u5v_5
Snippet: patients. The concentrations of 6 serum biochemical markers showed significant differences between severe and mild COVID-19 patients. Interestingly, the levels of serum biomarkers reflecting glomerular filtration function (including cystatin C (CysC), creatinine (CREA), and urea) in severe COVID-19 patients were significantly higher than those in mild patients. It has been demonstrated that serum urea, CREA and CysC could be potential biomarkers .....
Document: patients. The concentrations of 6 serum biochemical markers showed significant differences between severe and mild COVID-19 patients. Interestingly, the levels of serum biomarkers reflecting glomerular filtration function (including cystatin C (CysC), creatinine (CREA), and urea) in severe COVID-19 patients were significantly higher than those in mild patients. It has been demonstrated that serum urea, CREA and CysC could be potential biomarkers that could rapidly and specifically reflect severe COVID-19, and it is of great significance in the early diagnosis of COVID-19 to reduce the mortality and shorten the hospitalization period for patients with severe COVID-19. Moreover, glomerular filtration injury in patients with severe COVID-19 should not be ignored by clinicians.
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