Author: Wu Liu; Mehmet U. Caglar; Zhangming Mao; Andrew Woodman; Jamie J. Arnold; Claus O. Wilke; Craig E. Cameron
Title: More than efficacy revealed by single-cell analysis of antiviral therapeutics Document date: 2019_4_12
ID: aiyg061l_19
Snippet: Tables S9 and S10. Because 2'-C-Me-A exhibits the most substantial antiviral effect relative to 226 the DMS0 control, here we compare the combination to 2'-C-Me-A alone. We observed a 227 statistically significant difference for all parameters (Figs. 4b -4f ). Single-cell analysis therefore 228 has the ability to reveal efficacy of drug combinations masked at the population level. We 229 performed the comparable experiment with GS and reached the.....
Document: Tables S9 and S10. Because 2'-C-Me-A exhibits the most substantial antiviral effect relative to 226 the DMS0 control, here we compare the combination to 2'-C-Me-A alone. We observed a 227 statistically significant difference for all parameters (Figs. 4b -4f ). Single-cell analysis therefore 228 has the ability to reveal efficacy of drug combinations masked at the population level. We 229 performed the comparable experiment with GS and reached the same conclusion (Fig. S7 , Tables 230 S10 and S11). 231 All rights reserved. No reuse allowed without permission.
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