Author: Wu Liu; Mehmet U. Caglar; Zhangming Mao; Andrew Woodman; Jamie J. Arnold; Claus O. Wilke; Craig E. Cameron
Title: More than efficacy revealed by single-cell analysis of antiviral therapeutics Document date: 2019_4_12
ID: aiyg061l_25
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/606715 doi: bioRxiv preprint redesigned the device to add physical cell-trapping structures to each well. The outcome of 282 which is the ability to achieve single-cell occupancy of ~90% of the ~6000 wells of the device 283 (Figs. 1, S1-S3) . The enhanced occupancy enabled the complete characterization of antiviral 284 therapeutics.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. . https://doi.org/10.1101/606715 doi: bioRxiv preprint redesigned the device to add physical cell-trapping structures to each well. The outcome of 282 which is the ability to achieve single-cell occupancy of ~90% of the ~6000 wells of the device 283 (Figs. 1, S1-S3) . The enhanced occupancy enabled the complete characterization of antiviral 284 therapeutics by permitting the acquisition of complete dose-response curves (e.g. Fig. 2a) . 285
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