Selected article for: "airways gene expression and gene expression"

Author: Janice M Leung; Chen Xi Yang; Anthony Tam; Tawimas Shaipanich; Tillie L Hackett; Gurpreet K Singhera; Delbert R Dorscheid; Don D Sin
Title: ACE-2 Expression in the Small Airway Epithelia of Smokers and COPD Patients: Implications for COVID-19
  • Document date: 2020_3_23
  • ID: ei2b8oqn_13
    Snippet: In both the Cornell and BCCA cohorts, current smokers had increased ACE-2 gene expression levels in the airways compared with never smokers (in the Cornell cohort; Mean±SD of never smokers=4.15±0.36 versus current smokers=4.34±0.45, p=1.92×10 -3 ) and with former smokers (in the BCCA cohort; Mean±SD of former smokers=5.57±0.37 versus current smokers=6.05±0.53, p<2×10 -16 ). In the BCCA cohort, pre-bronchodilator FEV1 was measured and it w.....
    Document: In both the Cornell and BCCA cohorts, current smokers had increased ACE-2 gene expression levels in the airways compared with never smokers (in the Cornell cohort; Mean±SD of never smokers=4.15±0.36 versus current smokers=4.34±0.45, p=1.92×10 -3 ) and with former smokers (in the BCCA cohort; Mean±SD of former smokers=5.57±0.37 versus current smokers=6.05±0.53, p<2×10 -16 ). In the BCCA cohort, pre-bronchodilator FEV1 was measured and it was significantly related to ACE-2 gene expression level (r=-0.10;p=0.037).

    Search related documents:
    Co phrase search for related documents