Author: Scully, Eileen P.; Gupta, Amita; Klein, Sabra L.
Title: Sex-biased clinical presentation and outcomes from COVID-19 Cord-id: k6r2n6up Document date: 2021_4_1
ID: k6r2n6up
Snippet: Males are disproportionately affected by severe disease and death from SARS-CoV-2 infection. In their recent article, Mussini et al. found that among people admitted with severe COVID-19, males had higher biomarkers of peripheral inflammation and were more likely to require invasive mechanical ventilation and die from COVID-19 than females. These findings provide evidence that the clinical progression of COVID-19, including development of respiratory failure, is worse for males than females. Gre
Document: Males are disproportionately affected by severe disease and death from SARS-CoV-2 infection. In their recent article, Mussini et al. found that among people admitted with severe COVID-19, males had higher biomarkers of peripheral inflammation and were more likely to require invasive mechanical ventilation and die from COVID-19 than females. These findings provide evidence that the clinical progression of COVID-19, including development of respiratory failure, is worse for males than females. Greater consideration of sex a biological variable is needed in studies of COVID-19 outcomes and even vaccination.
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