Selected article for: "acute respiratory syndrome and lung pattern"
Author: Carlotti, Ana Paula de Carvalho Panzeri; de Carvalho, Werther Brunow; Johnston, Cíntia; Gilio, Alfredo Elias; de Sousa Marques, Heloisa Helena; Ferranti, Juliana Ferreira; Rodriguez, Isadora Souza; Delgado, Artur Figueiredo
Title: Update on the diagnosis and management of COVID-19 in pediatric patients
  • Cord-id: lit01j7w
  • Document date: 2020_11_25
    • ID: lit01j7w
    Snippet: Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a pandemic in March 2020, affecting millions of people worldwide. However, COVID-19 in pediatric patients represents 1-5% of all cases, and the risk for developing severe disease and critical illness is much lower in children with COVID-19 than in adults. Multisystem inflammatory syndrome in children (MIS-C), a possible complication of COVID-19, has been described as a hyperinflammatory
    Document: Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a pandemic in March 2020, affecting millions of people worldwide. However, COVID-19 in pediatric patients represents 1-5% of all cases, and the risk for developing severe disease and critical illness is much lower in children with COVID-19 than in adults. Multisystem inflammatory syndrome in children (MIS-C), a possible complication of COVID-19, has been described as a hyperinflammatory condition with multiorgan involvement similar to that in Kawasaki disease or toxic shock syndrome in children with evidence of SARS-CoV-2 infection. This review presents an update on the diagnostic methods for COVID-19, including reverse-transcriptase polymerase chain reaction (RT-PCR) tests, serology tests, and imaging, and summarizes the current recommendations for the management of the disease. Particular emphasis is placed on respiratory support, which includes noninvasive ventilation and invasive mechanical ventilation strategies according to lung compliance and pattern of lung injury. Pharmacological treatment, including pathogen-targeted drugs and host-directed therapies, has been addressed. The diagnostic criteria and management of MIS-C are also summarized.

    Search related documents:
    Co phrase search for related documents
    • abdominal pain and active infection: 1, 2, 3
    • abdominal pain and acute ards respiratory distress syndrome: 1, 2, 3, 4
    • abdominal pain and acute infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • abdominal pain and acute phase: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • abdominal pain and acute respiratory failure: 1, 2, 3, 4, 5, 6
    • abdominal pain and adenovirus respiratory syncytial virus: 1, 2
    • abdominal pain and adenovirus respiratory syncytial virus parainfluenza virus: 1, 2
    • active bleeding and acute ards respiratory distress syndrome: 1, 2
    • active infection and acute ards respiratory distress syndrome: 1, 2, 3, 4
    • active infection and acute hypoxemic respiratory failure: 1
    • active infection and acute infection: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • active infection and acute phase: 1, 2, 3, 4, 5, 6, 7
    • active infection and acute respiratory failure: 1, 2, 3, 4, 5
    • active infection and adenovirus respiratory syncytial virus: 1
    • acute ards respiratory distress syndrome and adenovirus respiratory syncytial virus: 1
    • acute ards respiratory distress syndrome and adolescent child: 1
    • acute infection and adenovirus respiratory syncytial virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute infection and adenovirus respiratory syncytial virus parainfluenza virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
    • acute infection and adolescent child: 1, 2