A Validation Study for the Successful Isolation Policy in China: a Meta-Analysis in COVID-19

Jianghu Dong; Yongdao Zhou; Ying Zhang; Douglas Franz

reached a buffer period by using early and aggressive quarantine measures, Most 75 of Europe is currently at its peak period, and the US remains in a period of 76 exponential case growth which may be due to late, inconsistent, and relatively 77 permissive isolation measures enacted by states in absence of an early unified 78 federal response. 79 The number of people who are infected during the peak period depends mainly 80 on the efficacy of quarantine in the absence of a vaccine. So the quarantine has 81 been carried out to decrease the effective reproduction number of COVID-19. 82 From the term of epidemic principles, the virus usually has the initial basic trans-83 missibility R 0 . R 0 is an important index to determine the epidemic intensity. So 84 many studies have been carried out to estimate it as we describe in detail below. 85 As the efficacy of quarantine increases, the reproductive number decrease. If the 86 declining trend continues with the assumption of no resurges of the epidemic, 87 the reproduction number will drop below one, meaning that each individual will, We introduce the related statistical models to solve the question in COVID-19 research in this section. Each virus has a basic reproductive index of R 0 . The All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.