Author: Caroline X. Gao; Yuguo Li; Jianjian Wei; Sue Cotton; Matthew Hamilton; Lei Wang; Benjamin J Cowling
Title: Multi-route respiratory infection: when a transmission route may dominate Document date: 2020_4_11
ID: mfnzkvd0_7
Snippet: Observational studies of existing outbreaks often fail to capture important time relevant evidence. A more feasible approach is to use mathematical models to describe the multi-route transmission using known parameters such as droplet generation rate, virus shedding rate, and virus survival rates. A few mathematical studies have developed multi-route transmission models such as by Nicas and Jones (18) , Atkinson and Wein (19) and Spicknall and co.....
Document: Observational studies of existing outbreaks often fail to capture important time relevant evidence. A more feasible approach is to use mathematical models to describe the multi-route transmission using known parameters such as droplet generation rate, virus shedding rate, and virus survival rates. A few mathematical studies have developed multi-route transmission models such as by Nicas and Jones (18) , Atkinson and Wein (19) and Spicknall and colleagues (20) . However, many critical factors, such as evaporation of respiratory droplets, travelling of the large droplets in the respiratory jet, pulmonary deposition, dose-response rate for different route were not fully evaluated in these models, which may underestimate the role of smaller droplets.
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