Author: GeurtsvanKessel, Corine H.; OKBA, NISREEN M.A.; Igloi, Zsofia; Embregts, Carmen W.E.; Laksono, Brigitta M.; Leijten, Lonneke; Rahamat-Langendoen, Janette; van den Akker, Johannes P.C.; van Kampen, Jeroen J.A.; van der Eijk, Annemiek A.; van Binnendijk, Rob S.; Hangman, Bart; Koopmans, Marion
Title: Towards the next phase: evaluation of serological assays for diagnostics and exposure assessment. Cord-id: nxy21x7k Document date: 2020_4_29
ID: nxy21x7k
Snippet: The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a comprehensive comparison of serological COVID-19 assays. We show that the assay detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, had optimal characteristics for antibody detection in different stages of disease.
Document: The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a comprehensive comparison of serological COVID-19 assays. We show that the assay detecting total immunoglobulins against the receptor binding domain of SARS CoV-2, had optimal characteristics for antibody detection in different stages of disease.
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