Author: Elhence, Anshuman; Mahapatra, Soumya Jagannath; Vajpai, Tanmay; Garg, Pramod Kumar
Title: Acute pancreatitis and nosocomial COVID-19: Cause specific host responses may determine lung injury Cord-id: lvx9iv8s Document date: 2020_8_19
ID: lvx9iv8s
Snippet: BACKGROUND: /ObjectivesCoronavirus disease 2019 (COVID-19) presents with myriad extra-pulmonary manifestation and a high mortality in patients with comorbidities. Its effect on patients with pre-existing severe acute pancreatitis is not known. METHODS: We hereby, present 3 cases with severe acute pancreatitis with persistent respiratory failure who acquired nosocomial COVID-19 during their hospital stay after recovery from respiratory failure. Their clinical course is highlighted which might ref
Document: BACKGROUND: /ObjectivesCoronavirus disease 2019 (COVID-19) presents with myriad extra-pulmonary manifestation and a high mortality in patients with comorbidities. Its effect on patients with pre-existing severe acute pancreatitis is not known. METHODS: We hereby, present 3 cases with severe acute pancreatitis with persistent respiratory failure who acquired nosocomial COVID-19 during their hospital stay after recovery from respiratory failure. Their clinical course is highlighted which might reflect on pathophysiology of organ dysfunction. RESULTS: None of the 3 patients with severe acute pancreatitis who developed nosocomial COVID-19 redeveloped respiratory failure suggestive of severe COVID-19 despite having recently recovered from pancreatitis induced acute hypoxemic respiratory failure. Only one patient had SARS-CoV2 induced moderate pneumonia. CONCLUSION: These cases highlight that host responses and mechanisms of lung injury might be different in severe pancreatitis and COVID-19.
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