Author: Cassius, C.; Merandet, M.; Frumholtz, L.; Bergerat, D.; Samri, A.; Grolleau, C.; Grzelak, L.; Schwartz, O.; Yatim, N.; Moghadam, P.; Jaume, L.; Bagot, M.; Legoff, J.; Delaugerre, C.; Bouaziz, J.â€D.; Le Buanec, H.
                    Title: Analysis of Tâ€cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in patients with chilblainâ€like lesions during the COVIDâ€19 pandemic  Cord-id: lw2zha79  Document date: 2021_9_7
                    ID: lw2zha79
                    
                    Snippet: A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic 1 . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy 2 which was further questioned 3 . An indirect link was highlighted with high prev
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic 1 . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy 2 which was further questioned 3 . An indirect link was highlighted with high prevalence of seropositivity in CLL patients compared to general population 4 .
 
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