Author: Togano, Tomiteru; Uemura, Yukari; Asai, Yusuke; Hayakawa, Kayoko; Matsunaga, Nobuaki; Terada, Mari; Ohtsu, Hiroshi; Suzuki, Setsuko; Toyoda, Ako; Hara, Hisao; Sato, Rubuna; Ishikane, Masahiro; Kinoshita-Iwamoto, Noriko; Hangaishi, Akira; Ohmagari, Norio
Title: The influence of pre-admission antiplatelet and anticoagulation therapy on the illness severity in hospitalized patients with COVID-19 in Japan Cord-id: o48bla44 Document date: 2021_7_24
ID: o48bla44
Snippet: INTRODUCTION: Many articles have reported that the coronavirus disease 2019 (COVID-19) causes coagulation abnormalities and pulmonary thrombosis, contributing to a poorer prognosis. The study aimed to evaluate whether pre-admission anticoagulation and antiplatelet therapy prevented severe COVID-19 illness or not. MATERIALS AND METHODS: We conducted a study to determine whether taking antiplatelet or anticoagulation agents before admission affected the severity on admission using a large nationwi
Document: INTRODUCTION: Many articles have reported that the coronavirus disease 2019 (COVID-19) causes coagulation abnormalities and pulmonary thrombosis, contributing to a poorer prognosis. The study aimed to evaluate whether pre-admission anticoagulation and antiplatelet therapy prevented severe COVID-19 illness or not. MATERIALS AND METHODS: We conducted a study to determine whether taking antiplatelet or anticoagulation agents before admission affected the severity on admission using a large nationwide cohort of hospitalized COVID-19 patients in Japan. We analyzed a large nationwide cohort of hospitalized COVID-19 patients in Japan from February 9 to July 31, 2020. RESULTS AND CONCLUSION: A total of 4265 patients from 342 facilities in Japan were included. Their use was associated with a slight reduction in the disease severity on admission in a propensity score-matched analysis which controlled for underlying diseases. However, this difference was not statistically significant.
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