Selected article for: "drug target and therapeutic approach"

Author: Neha Jain; Subodh Kumar Mishra; Uma Shankar; Arpita Tawani; Ankit Jaiswal; Tarun Kumar Sharma; Prashant Kodgire; Amit Kumar
Title: G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence
  • Document date: 2018_6_27
  • ID: 57xx291v_14
    Snippet: All these reports demonstrated the pivotal role of G-quadruplex in human pathogens and their conserved-ness suggest them as a promising drug target for both drug susceptible and drug-resistant strains of human pathogens. Therefore, a comprehensive study that discovers highly conserved Gquadruplex in the genome of S. enterica as a drug target may provide as a most suitable therapeutic approach for fighting against the infection of this deadly path.....
    Document: All these reports demonstrated the pivotal role of G-quadruplex in human pathogens and their conserved-ness suggest them as a promising drug target for both drug susceptible and drug-resistant strains of human pathogens. Therefore, a comprehensive study that discovers highly conserved Gquadruplex in the genome of S. enterica as a drug target may provide as a most suitable therapeutic approach for fighting against the infection of this deadly pathogen and overcome the emergence of drugresistant problem in this bacterium.

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