Author: Neha Jain; Subodh Kumar Mishra; Uma Shankar; Arpita Tawani; Ankit Jaiswal; Tarun Kumar Sharma; Prashant Kodgire; Amit Kumar
Title: G-quadruplex stabilization in the ions and maltose transporters inhibit Salmonella enterica growth and virulence Document date: 2018_6_27
ID: 57xx291v_17
Snippet: As mentioned above, these genes are essential for bacterial survival and virulence inside the host macrophages. Therefore, G-quadruplex motifs found in these genes can be utilized as a potential drug target to develop a promising anti-microbial therapeutics. Moreover, the high conserved-ness of these SE-PGQs, even in the drug-resistant strain would overcome the problem of emergence of drug-resistance in S. enterica......
Document: As mentioned above, these genes are essential for bacterial survival and virulence inside the host macrophages. Therefore, G-quadruplex motifs found in these genes can be utilized as a potential drug target to develop a promising anti-microbial therapeutics. Moreover, the high conserved-ness of these SE-PGQs, even in the drug-resistant strain would overcome the problem of emergence of drug-resistance in S. enterica.
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