Selected article for: "Bat cov and Human SARS cov"
Author: Aiping Wu; Peihua Niu; Lulan Wang; Hangyu Zhou; Xiang Zhao; Wenling Wang; Jingfeng Wang; Chengyang Ji; Xiao Ding; Xianyue Wang; Roujian Lu; Sarah Gold; Saba Aliyari; Shilei Zhang; Ellee Vikram; Angela Zou; Emily Lenh; Janet Chen; Fei Ye; Na Han; Yousong Peng; Haitao Guo; Guizhen Wu; Taijiao Jiang; Wenjie Tan; Genhong Cheng
Title: Mutations, Recombination and Insertion in the Evolution of 2019-nCoV
  • Document date: 2020_3_2
    • ID: jmrg4oeb_20
    Snippet: The 2019-nCoV is still spreading rapidly from Wuhan to different cities in China and other countries, at a magnitude faster than SARS and MERS 4 . We have systematically analyzed and tracked the genome mutations among 120 different strains of 2019-nCoV. Although most substitutions are de novo mutations, we have identified 2019-nCoV as a member of the betacoronaviruses, shares similar genome structures as bat SARS, human SARS, MERS with nucleotide.....
    Document: The 2019-nCoV is still spreading rapidly from Wuhan to different cities in China and other countries, at a magnitude faster than SARS and MERS 4 . We have systematically analyzed and tracked the genome mutations among 120 different strains of 2019-nCoV. Although most substitutions are de novo mutations, we have identified 2019-nCoV as a member of the betacoronaviruses, shares similar genome structures as bat SARS, human SARS, MERS with nucleotide identity over 88%, 79%, about and 50%,respectively 23 . Its closest relative is the Beta CoV RaTG13, isolated from 20 bat in Yunnan province, China, in 2013, which shares more than 96% identical nucleotides throughout the genome of over 30 kb 15,24 . Our evolution clock analysis estimated that 2019-nCoV diverged from RaTG13 and human SARS-CoV at about 12 author/funder. All rights reserved. No reuse allowed without permission.

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