Author: Bascuñana., Arturo; Mijaylova., Antonia; Vega, Almudena; MacÃas, Nicolás; Verde, Eduardo; RodrÃguez-Ferrero, Maria Luisa; Delgado, Andrés; Carbayo, Javier; Goicoechea, Marian
Title: Thrombotic Microangiopathy in a Kidney Transplant Patient With COVID-19 Cord-id: m4s3gtmk Document date: 2020_12_10
ID: m4s3gtmk
Snippet: Kidney transplant recipients are at increased risk of infection, including COVID-19, given ongoing immunosuppression. In individuals with COVID-19, complications including thrombosis and endothelial dysfunction, portend worse outcomes. In this report, we describe a kidney transplant recipient who developed severe thrombotic microangiopathy (TMA) with low platelet count (12 x 109 /L), anemia (7.5g/dL with 7% schistocytes on peripheral blood smear) and severe acute kidney injury concurrent with CO
Document: Kidney transplant recipients are at increased risk of infection, including COVID-19, given ongoing immunosuppression. In individuals with COVID-19, complications including thrombosis and endothelial dysfunction, portend worse outcomes. In this report, we describe a kidney transplant recipient who developed severe thrombotic microangiopathy (TMA) with low platelet count (12 x 109 /L), anemia (7.5g/dL with 7% schistocytes on peripheral blood smear) and severe acute kidney injury concurrent with COVID-19. The clinical course improved following plasma exchange. Given this presentation, we hypothesize that COVID-19 triggered TMA.
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