Author: S. Willis; J. Masel
Title: Gene birth contributes to structural disorder encoded by overlapping genes Document date: 2017_12_6
ID: 9w2wjiik_26
Snippet: Second, for the frameshifted ORF controls, we took only in situ ORFs within each of the two alternative reading frames. If multiple ORFs terminated at the same stop codon, we used only the longest. We excluded ORFs less than 25 amino acids in length (after removal of cysteines for analysis by IUPred). For nonoverlapping genes, this yielded 151 and 24 ORFs in the +1 and +2 reading frames, respectively. For the smaller set of pre-overlapping genes,.....
Document: Second, for the frameshifted ORF controls, we took only in situ ORFs within each of the two alternative reading frames. If multiple ORFs terminated at the same stop codon, we used only the longest. We excluded ORFs less than 25 amino acids in length (after removal of cysteines for analysis by IUPred). For nonoverlapping genes, this yielded 151 and 24 ORFs in the +1 and +2 reading frames, respectively. For the smaller set of pre-overlapping genes, it yielded only 25 and 5 ORFs in the +1 and +2 frames, respectively. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/229690 doi: bioRxiv preprint
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