BrainCheck: Validation of a Computerized Cognitive Test Battery for Detection of Mild Cognitive Impairment and Dementia

Ye, S.; Huang, B.; Sun, K.; Phi, H.; Ko, B.; Parsey, C. M.; Hosseini Ghomi, R.

INTRODUCTION: Early detection of dementia is critical for intervention and care planning, but remains difficult. This study evaluated a computerized cognitive testing battery (BrainCheck) for its diagnostic accuracy and ability to distinguish the severity of cognitive impairment. METHODS: 99 participants diagnosed with Dementia, Mild Cognitive Impairment (MCI), or Normal Cognition (NC) completed the BrainCheck battery. Statistical analyses compared participants performance on BrainCheck based on their diagnosis group. RESULTS: BrainCheck battery performance showed significant differences between the NC, MCI, and Dementia groups, achieving >88% sensitivity/specificity for separating NC from Dementia, and >77% sensitivity/specificity in separating the MCI group from NC/Dementia groups. Three-group-classification found true positive rates >80% for the NC and Dementia groups and >60% for the MCI group. DISCUSSION: BrainCheck was able to distinguish between diagnoses of Dementia, MCI, and NC, providing a potentially reliable tool for early detection of cognitive impairment.