Author: Jerome R Lon; Yunmeng Bai; Bingxu Zhong; Fuqiang Cai; Hongli Du
Title: Prediction and Evolution of B Cell Epitopes of Surface Protein in SARS-CoV-2 Document date: 2020_4_5
ID: fmumym1x_2
Snippet: The B cell epitope of viral surface protein can specifically bind to the host's B cell antigen receptor and induce the body to produce protective antibody and humoral immune response. The discovery of epitopes is helpful to the development of SARS-CoV-2 vaccine and the understanding of SARS-CoV-2's pathogenesis [3] . 3 proteins embedded in the virus envelope of SARS-CoV-2 have been identified, Spike(S) protein, Envelope(E) protein, Membrane(M) pr.....
Document: The B cell epitope of viral surface protein can specifically bind to the host's B cell antigen receptor and induce the body to produce protective antibody and humoral immune response. The discovery of epitopes is helpful to the development of SARS-CoV-2 vaccine and the understanding of SARS-CoV-2's pathogenesis [3] . 3 proteins embedded in the virus envelope of SARS-CoV-2 have been identified, Spike(S) protein, Envelope(E) protein, Membrane(M) protein. At present, due to the lack of study of the crystal structure of surface protein of SARS-CoV-2, the study of epitopes is timeconsuming, power-consuming, cost and difficult [4] .
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