Author: Zheng Zhang; Sifan Ye; Aiping Wu; Taijiao Jiang; Yousong Peng
Title: Prediction of receptorome for human-infecting virome Document date: 2020_2_28
ID: 9ruhvpbv_2
Snippet: Previous studies have shown that proteins that were abundant in the host cell surface or had relatively low affinity for their natural ligands were preferred by viruses as receptors (Dimitrov, 2004; Wang, 2002) . Based on a collection of 119 mammalian virus receptors, our recent study further showed that human virus protein receptors have higher level of N-glycosylation, higher number of interaction partners in the human protein-protein interacti.....
Document: Previous studies have shown that proteins that were abundant in the host cell surface or had relatively low affinity for their natural ligands were preferred by viruses as receptors (Dimitrov, 2004; Wang, 2002) . Based on a collection of 119 mammalian virus receptors, our recent study further showed that human virus protein receptors have higher level of N-glycosylation, higher number of interaction partners in the human protein-protein interaction (PPI) network and high expressions in 32 common human tissues compared to other cell membrane proteins (Zhang et al., 2019) . These studies could facilitate identification of human virus receptors.
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