Selected article for: "receptor viral rbp and RF model"
Author: Zheng Zhang; Sifan Ye; Aiping Wu; Taijiao Jiang; Yousong Peng
Title: Prediction of receptorome for human-infecting virome
  • Document date: 2020_2_28
    • ID: 9ruhvpbv_27
    Snippet: When ranking the RBP-interacting proteins by the RF model, high sequence similarity between the RBP-interacting proteins and human proteins in the modeling (both the positive and negative samples) may over-estimate the ability of the RF model. To reduce such effect, for each pair of viral RBP and receptor, the predicted RBP-interacting human proteins were clustered with human proteins used in the modeling using CD-HIT at 50% identity level. All p.....
    Document: When ranking the RBP-interacting proteins by the RF model, high sequence similarity between the RBP-interacting proteins and human proteins in the modeling (both the positive and negative samples) may over-estimate the ability of the RF model. To reduce such effect, for each pair of viral RBP and receptor, the predicted RBP-interacting human proteins were clustered with human proteins used in the modeling using CD-HIT at 50% identity level. All proteins which were clustered with RBP-interacting proteins were excluded in the modeling.

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