Author: Tayaza Fadason; Sreemol Gokuladhas; Evgeniia Golovina; Daniel Ho; Sophie Farrow; Denis Nyaga; Hong Pan; Neerja Karnani; Conroy Wong; Antony Cooper; William Schierding; Justin M. O’Sullivan
Title: A transcription regulatory network within the ACE2 locus may promote a pro-viral environment for SARS-CoV-2 by modulating expression of host factors Document date: 2020_4_15
ID: 5r0u2mmo_4
Snippet: Results: We identified regulatory elements within ACE2 that control the expression of PIR, 36 CA5B, and VSP13C in the lung. The gene products of these genes are involved in inflammatory 37 responses, de novo pyrimidine and polyamine synthesis, and the endoplasmic reticulum, 38.....
Document: Results: We identified regulatory elements within ACE2 that control the expression of PIR, 36 CA5B, and VSP13C in the lung. The gene products of these genes are involved in inflammatory 37 responses, de novo pyrimidine and polyamine synthesis, and the endoplasmic reticulum, 38
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