Potentially highly potent drugs for 2019-nCoV

Duc Duy Nguyen; Kaifu Gao; Jiahui Chen; Rui Wang; Guo-Wei Wei

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.05.936013 doi: bioRxiv preprint relaxant properties. The third one, Ponatinib, an oral drug for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia, which is a multi-targeted tyrosine kinase inhibitor. It is important to notice that this drug has the risk of life-threatening blood clots and severe narrowing of blood vessels. The next one is Sorafenib, a kinase inhibitor for the treatment of primary kidney cancer and liver cancer. The fifth drug, Dasatinib, is a therapy for treating certain cases of chronic myelogenous leukemia and acute lymphoblastic leukemia. The next one, Paramethasone, is a glucocorticoid with the general properties of corticosteroids. The seventh drug is Clocortolone, a topical steroid that is used in the form of an ester, clocortolone pivalate. It is interesting to note that this drug is always applied as a cream for the treatment of dermatitis. It is considered a medium-strength corticosteroid. Therefore, this drug might be used to clean 2019-nCoV contaminated materials, offering an extra layer of protection. The number eight drug, Flucloxacillin, is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. The next one, Sertindole, is an antipsychotic medication. The number ten drug, Clevidipine, is a dihydropyridine calcium channel blocker that used for the reduction of blood pressure when oral therapy is not feasible or not desirable. The eleventh drug, Aprepitant, is used to prevent chemotherapy-induced nausea and vomiting, as well as postoperative nausea and vomiting. The number twelve, Atorvastatin, is a statin drug used to prevent cardiovascular disease in those at high risk and treat abnormal lipid levels. The next drug is Cinolazepam, a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative, and skeletal muscle relaxant properties. The number fourteen drug, Clofazimine, is used together with rifampicin and dapsone to treat leprosy. The fifteenth number drug, Fosaprepitant, is an antiemetic medication used in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.