Author: Ethan Fast; Russ B. Altman; Binbin Chen
Title: Potential T-cell and B-cell Epitopes of 2019-nCoV Document date: 2020_2_21
ID: j6y806qu_11
Snippet: Our pipeline provides a framework to identify strong 303 epitope-based vaccine candidates and might be applied against 304 any unknown pathogens. We were able to model structures 305 of 2019-nCoV spike protein as soon as the DNA sequence be-306 came available, and the modeled structure has high similarity 307 with later solved crystal structures (SI Appendix, Fig. S1 ). 308 This suggests the researchers can rely on homology remodeling 309 when em.....
Document: Our pipeline provides a framework to identify strong 303 epitope-based vaccine candidates and might be applied against 304 any unknown pathogens. We were able to model structures 305 of 2019-nCoV spike protein as soon as the DNA sequence be-306 came available, and the modeled structure has high similarity 307 with later solved crystal structures (SI Appendix, Fig. S1 ). 308 This suggests the researchers can rely on homology remodeling 309 when emerging pathogens first appear if the new pathogen 310 shares high sequence similarity with an existing pathogen.
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