Selected article for: "certain disease process and disease process"
Author: Mehdi Baratchian; Jeff McManus; Mike Berk; Fumihiko Nakamura; Serpil Erzurum; Sanjay Mukhopadhyay; Judy Drazba; John Peterson; Ben Gaston; Nima Sharifi
Title: No evidence that androgen regulation of pulmonary TMPRSS2 explains sex-discordant COVID-19 outcomes
  • Document date: 2020_4_21
    • ID: awb1stsr_11
    Snippet: harbors an AR-responsive enhancer that is induced by male gonadal hormones in prostate tissue (Wang et al., 2007) , raising the possibility of a similar mode of regulation in the respiratory system. Furthermore, certain pulmonary disease process outcomes, including asthma, are sex steroid associated (Zein et al., 2020) . Therefore, we sought to investigate whether male sex was associated with higher expression of TMPRSS2 or AR in human lung......
    Document: harbors an AR-responsive enhancer that is induced by male gonadal hormones in prostate tissue (Wang et al., 2007) , raising the possibility of a similar mode of regulation in the respiratory system. Furthermore, certain pulmonary disease process outcomes, including asthma, are sex steroid associated (Zein et al., 2020) . Therefore, we sought to investigate whether male sex was associated with higher expression of TMPRSS2 or AR in human lung.

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