Author: Matthijs Kox; Tim Frenzel; Jeroen Schouten; Frank van de Veerdonk; Hans J.P.M. Koenen; Peter Pickkers
Title: No indications for overt innate immune suppression in critically ill COVID-19 patients Document date: 2020_4_6
ID: 3ngrtmb0_4
Snippet: The ethics committee (CMO Arnhem-Nijmegen) board waived the need for informed consent because of the observational nature of the study and the non-invasiveness of blood withdrawal (all patients had an arterial canula in place, so no venapunctures were performed). All patients or legal representatives were informed about the study details and allowed to abstain from participation. Ethylenediaminetetraacetic acid (EDTA)-anticoagulated blood was sto.....
Document: The ethics committee (CMO Arnhem-Nijmegen) board waived the need for informed consent because of the observational nature of the study and the non-invasiveness of blood withdrawal (all patients had an arterial canula in place, so no venapunctures were performed). All patients or legal representatives were informed about the study details and allowed to abstain from participation. Ethylenediaminetetraacetic acid (EDTA)-anticoagulated blood was stored at 4-8 o C until mHLA-DR expression analysis (performed within 2 hours after withdrawal). the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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