Author: Alessandra Renieri; Elisa Benetti; Rossella Tita; Ottavia Spiga; Andrea Ciolfi; Giovanni Birolo; Alessandro Bruselles; Gabriella Doddato; Annarita Giliberti; Cterina Marconi; Francesco Musacchia; Tommaso Pippucci; Annalaura Torella; Alfonso Trezza; Floriana Valentino; Mrgherita Baldassarri; Alfredo Brusco; Rosanna Asselta; Bruttini Mirella; Simone Furini; Marco Seri; Vincenzo Nigro; Giuseppe Matullo; Marco Tartaglia; Francesca Mari; Annamaria Pinto
Title: ACE2 variants underlie interindividual variability and susceptibility to COVID-19 in Italian population Document date: 2020_4_6
ID: klj710h2_17
Snippet: Similarly, p.Trp69Cys, p.Leu351Val and p.Pro389His, which affects a highly hydrophobic core, were predicted to induce conformational changes influencing the interaction with spike protein. The aminoacidic substitution p.Pro389His (rs762890235, European-non Finnish population allele frequency: 0.00002453, cadd 24,8) was All rights reserved. No reuse allowed without permission......
Document: Similarly, p.Trp69Cys, p.Leu351Val and p.Pro389His, which affects a highly hydrophobic core, were predicted to induce conformational changes influencing the interaction with spike protein. The aminoacidic substitution p.Pro389His (rs762890235, European-non Finnish population allele frequency: 0.00002453, cadd 24,8) was All rights reserved. No reuse allowed without permission.
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