Author: Bo Ram Beck; Bonggun Shin; Yoonjung Choi; Sungsoo Park; Keunsoo Kang
Title: Predicting commercially available antiviral drugs that may act on the novel coronavirus (2019-nCoV), Wuhan, China through a drug-target interaction deep learning model Document date: 2020_2_2
ID: cszqykpu_6
Snippet: Amino acid sequences of 3C-like proteinase (accession YP_009725301.1), RNA-dependent RNA polymerase (accession YP_009725307.1), helicase (accession YP_009725308.1), 3'-to-5' exonuclease (accession YP_009725309.1), endoRNAse (accession YP_009725310.1), and 2'-O-ribose methyltransferase (accession YP_009725311.1) of the 2019-nCoV replication complex were extracted from the 2019-nCoV whole genome sequence (accession NC_045512.2), from the National C.....
Document: Amino acid sequences of 3C-like proteinase (accession YP_009725301.1), RNA-dependent RNA polymerase (accession YP_009725307.1), helicase (accession YP_009725308.1), 3'-to-5' exonuclease (accession YP_009725309.1), endoRNAse (accession YP_009725310.1), and 2'-O-ribose methyltransferase (accession YP_009725311.1) of the 2019-nCoV replication complex were extracted from the 2019-nCoV whole genome sequence (accession NC_045512.2), from the National Center for Biotechnology Information (NCBI) database. The raw prediction results were screened for antiviral drugs that are FDA approved, target viral proteins, and have a Kd value less than 1,000 nM.
Search related documents:
Co phrase search for related documents- accession ribose methyltransferase and antiviral drug: 1
- accession ribose methyltransferase and ribose methyltransferase: 1
- accession RNA dependent RNA polymerase and RNA dependent RNA polymerase: 1
- accession RNA dependent RNA polymerase and RNA polymerase: 1
- Amino acid and antiviral drug: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30
- Amino acid and Biotechnology Information National Center NCBI database: 1, 2, 3, 4
- Amino acid and genome sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76
- Amino acid and Kd value: 1
- Amino acid and NCBI database: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41
- Amino acid and replication complex: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29
- Amino acid and ribose methyltransferase: 1, 2
- Amino acid and RNA dependent RNA polymerase: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- Amino acid and RNA polymerase: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- Amino acid and viral protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77
- Amino acid and viral protein target: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- Amino acid sequence and antiviral drug: 1, 2, 3, 4, 5
- Amino acid sequence and Biotechnology Information National Center NCBI database: 1
- Amino acid sequence and genome sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57
- Amino acid sequence and NCBI database: 1, 2, 3, 4, 5, 6, 7
Co phrase search for related documents, hyperlinks ordered by date