Selected article for: "SARS spike and structure model"
Author: Zehua Zeng; Zhi Luo; Hongwu Du
Title: Predictions for the binding domain and potential new drug targets of 2019-nCoV
  • Document date: 2020_3_2
    • ID: fvig79k3_29
    Snippet: In this study, the nucleotide interval of the surface glycoprotein of the 2019-nCoV was analyzed and it was similar to the spike interval of SARS-CoV 8 . Three-dimensional structure prediction of protein showed that the prediction model with the highest score in I-TASSER was comparable to the 5x58 spike protein electron microscope results, and the prediction model with the highest score in phyre2 was comparable to the 5x5b SARS-CoV spike protein......
    Document: In this study, the nucleotide interval of the surface glycoprotein of the 2019-nCoV was analyzed and it was similar to the spike interval of SARS-CoV 8 . Three-dimensional structure prediction of protein showed that the prediction model with the highest score in I-TASSER was comparable to the 5x58 spike protein electron microscope results, and the prediction model with the highest score in phyre2 was comparable to the 5x5b SARS-CoV spike protein. Moreover, the prediction model in I-TASSER was highly similar to that in 5x58 which indirectly makes the nucleotide interval 2019-nCoV, indicating that the possibility of glycoprotein expression was increased again.

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