Author: Wang, Chunyan; Li, Wentao; Drabek, Dubravka; Okba, Nisreen M.A.; Haperen, Rien van; Osterhaus, Albert D.M.E.; Kuppeveld, Frank J.M. van; Haagmans, Bart L.; Grosveld, Frank; Bosch, Berend-Jan
Title: A human monoclonal 1 antibody blocking SARS-CoV-2 infection Cord-id: mlo8zypy Document date: 2020_3_12
ID: mlo8zypy
Snippet: The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.
Document: The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.
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