Selected article for: "cell response and inflammatory response"
Author: Alejandro Lopez-Rincon; Alberto Tonda; Lucero Mendoza-Maldonado; Eric Claassen; Johan Garssen; Aletta D. Kraneveld
Title: Accurate Identification of SARS-CoV-2 from Viral Genome Sequences using Deep Learning
  • Document date: 2020_3_14
    • ID: c2lljdi7_53
    Snippet: After deep learning analysis, we identify that the sequence TAGCACTCTC-255 CAAGGGTGTTC is exclusive for SARS-CoV-2 and shows a frequency of 100% in viral genomes available from different countries in the GISAID [37] and NCBI [22] . Using NC045512.2 as reference SARS-CoV-2 sequence, we identify this unique sequence is located from 25604 to 25624 nucleotides in ORF3a gene. In SARS-CoV, this gene encodes a protein of 274 aa, that is related with 260.....
    Document: After deep learning analysis, we identify that the sequence TAGCACTCTC-255 CAAGGGTGTTC is exclusive for SARS-CoV-2 and shows a frequency of 100% in viral genomes available from different countries in the GISAID [37] and NCBI [22] . Using NC045512.2 as reference SARS-CoV-2 sequence, we identify this unique sequence is located from 25604 to 25624 nucleotides in ORF3a gene. In SARS-CoV, this gene encodes a protein of 274 aa, that is related with 260 necrotic cell death [38] , chemokine production, inflammatory response [39] and may play an important role in virus life cycle [40] . With this information, we design a specific primer set for detection of SARS-CoV-2 using Primer3plus [41] .

    Search related documents:
    Co phrase search for related documents
    • cell death and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cell death and inflammatory response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cell death and learning analysis: 1, 2, 3, 4
    • cell death and SARS detection: 1, 2, 3
    • cell death and unique sequence: 1, 2
    • cell death and viral genome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • cell death and virus life: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • cell death and virus life cycle: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • chemokine production and important role: 1, 2
    • chemokine production and inflammatory response: 1, 2, 3, 4, 5, 6
    • chemokine production and viral genome: 1
    • chemokine production and virus life: 1
    • deep learning analysis and important role: 1, 2
    • deep learning analysis and learning analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • different country and important role: 1, 2, 3, 4
    • different country and SARS detection: 1, 2
    • different country and SARS sequence: 1
    • different country and viral genome: 1, 2
    • important role and virus life cycle: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18