Author: Ashish Goyal; E. Fabian Cardozo-Ojeda; Joshua T Schiffer
Title: Potency and timing of antiviral therapy as determinants of duration of SARS CoV-2 shedding and intensity of inflammatory response Document date: 2020_4_14
ID: d7stppv5_10
Snippet: We continuously quantified the value of the immune terms in all 25 participants: the per cell killing rate and total number of cells killed per day was extremely high during the first several days of infection in all participants (Fig. 2a, b) , coinciding with peak viral load. The cytolytic immune response initiated at various timepoints across participants (day 5-17) and led to lower per cell and total killing rates relative to the innate respon.....
Document: We continuously quantified the value of the immune terms in all 25 participants: the per cell killing rate and total number of cells killed per day was extremely high during the first several days of infection in all participants (Fig. 2a, b) , coinciding with peak viral load. The cytolytic immune response initiated at various timepoints across participants (day 5-17) and led to lower per cell and total killing rates relative to the innate response but was sufficient to eliminate remaining infection (Fig. 2b) .
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