Author: Alfano, Gaetano; Perrone, Rossella; Fontana, Francesco; Mori, Giacomo; Lucchi, Leonardo; Guaraldi, Giovanni; Magistroni, Riccardo; Cappelli, Gianni
                    Title: Longâ€term effects of COVIDâ€19 in a patient on maintenance dialysis  Cord-id: q49ktllj  Document date: 2020_8_2
                    ID: q49ktllj
                    
                    Snippet: Coronavirus infectious disease (COVIDâ€19) is a novel respiratory infection highly associated with severe complications in elderly subjects affected by cardiovascular disease. Patients on maintenance dialysis are exceptionally vulnerable because most of them are old and have multiple comorbidities. We report the complex clinical course of SARSâ€CoVâ€2 infection in a patient on maintenance dialysis who presented with fever and lung edema. After 41 days from the primary infection, the clinicall
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: Coronavirus infectious disease (COVIDâ€19) is a novel respiratory infection highly associated with severe complications in elderly subjects affected by cardiovascular disease. Patients on maintenance dialysis are exceptionally vulnerable because most of them are old and have multiple comorbidities. We report the complex clinical course of SARSâ€CoVâ€2 infection in a patient on maintenance dialysis who presented with fever and lung edema. After 41 days from the primary infection, the clinically recovered patient experienced symptomatic reactivation of SARSâ€COVâ€2 infection documented by positive polymerase chain reaction (PCR) result on nasal/oropharyngeal swab with immunoglobulin M seroconversion. The recurrence of PCR positivity forced us to perform hemodialysis in a separate isolation room for a prolonged period of time. Close monitoring of previously infected patients and restructuring of dialysis facilities are necessary to avoid new outbreaks of this concerning disease.
 
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