Author: Haoyan Chen; Baoqin Xuan; Yuqing Yan; Xiaoqiang Zhu; Chaoqin Shen; Gang Zhao; Linhua Ji; Danhua Xu; Hua Xiong; TaChung Yu; Xiaobo Li; Qiang Liu; Yingxuan Chen; Yun Cui; Jie Hong; Jing-Yuan Fang
Title: Profiling ACE2 expression in colon tissue of healthy adults and colorectal cancer patients by single-cell transcriptome analysis Document date: 2020_2_23
ID: 3r0nqzgu_17
Snippet: The copyright holder for this preprint . https://doi.org/10.1101/2020.02.15.20023457 doi: medRxiv preprint angiotensin converting enzyme II (ACE2), which was known as cell receptor for SARS-CoV (6). In addition, 2019-nCoV is able to enter lots of mammal cells with ACE2 receptor expression, but not cells without ACE2(6). Interestingly, 2019n-CoV just specifically uses ACE2 to infect mammal cells, but not other coronavirus receptor(6). Therefore AC.....
Document: The copyright holder for this preprint . https://doi.org/10.1101/2020.02.15.20023457 doi: medRxiv preprint angiotensin converting enzyme II (ACE2), which was known as cell receptor for SARS-CoV (6). In addition, 2019-nCoV is able to enter lots of mammal cells with ACE2 receptor expression, but not cells without ACE2(6). Interestingly, 2019n-CoV just specifically uses ACE2 to infect mammal cells, but not other coronavirus receptor(6). Therefore ACE2 receptor may be the key component for 2019-nCoV to infect human and transmit in the host body.
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