Selected article for: "Blueprint expert group and treatment effect"
Author: Maja von Cube; Marlon Grodd; Martin Wolkewitz; Derek Hazard; Jerome Lambert
Title: Harmonizing heterogeneous endpoints in COVID-19 trials without loss of information - an essential step to facilitate decision making
  • Document date: 2020_4_3
    • ID: bsddxgx2_14
    Snippet: The categorical endpoint recommended by the WHO R&D Blueprint expert group (7) ensures detailed collection of information on a range of important events. Nonetheless, a single estimate for the treatment effect -albeit an important summary of the benefit on the primary outcome -does not provide sufficient information. All time-dynamic aspects of the treatment must be understood in detail to make well-informed decisions. In light of the emergency, .....
    Document: The categorical endpoint recommended by the WHO R&D Blueprint expert group (7) ensures detailed collection of information on a range of important events. Nonetheless, a single estimate for the treatment effect -albeit an important summary of the benefit on the primary outcome -does not provide sufficient information. All time-dynamic aspects of the treatment must be understood in detail to make well-informed decisions. In light of the emergency, it is essential to exploit the full potential of all the available data to be able to report on all potential treatment effects.

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