Selected article for: "SARS infection and serological study"
Author: do Couto, Anahi Chechia; Kmetiuk, Louise Bach; Delai, Ruana Renostro; Brandão, Ana Pérola Drulla; Monteiro, Cairo Oliveira; da Silva, Luciana Helena Antoniassi; Soares, Camila; Banari, Alexandre Campos; Bach, Renato van Wilpe; Pettan-Brewer, Christina; dos Santos, Andrea Pires; Guimarães, Ana Marcia Sá; Oliveira, Danielle Bruna Leal; Durigon, Edison Luiz; Biondo, Alexander Welker
Title: High SARS-CoV-2 seroprevalence in persons experiencing homelessness and shelter workers from a day-shelter in São Paulo, Brazil
  • Cord-id: o0r6iq9e
  • Document date: 2021_10_19
    • ID: o0r6iq9e
    Snippet: Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly assess the molecular and serological prevalence and associated risk factors of SARS-CoV-2 infection in a homeless population and related shelter workers from a day-shelter. Serum samples, nasopharyngea
    Document: Brazil presents one of the highest COVID-19 death tolls in the world. The initial SARS-CoV-2 epicenter was São Paulo city. As of 2019, the homeless population of São Paulo city was estimated at 24,344 individuals, the largest national homeless population. The present study aimed to concomitantly assess the molecular and serological prevalence and associated risk factors of SARS-CoV-2 infection in a homeless population and related shelter workers from a day-shelter. Serum samples, nasopharyngeal and oropharyngeal swabs of persons who are homeless and shelter workers collected from August 25(th) to 27(th), 2020 were tested for the presence of anti-SARS-CoV-2 IgM and IgG antibodies by ELISA and SARS-CoV-2 RNA by RT-qPCR, respectively. All swab samples tested negative by RT-qPCR. Seropositivity of IgM and IgG was 5/203 (2.5%) and 111/203 (54.7%) in persons who are homeless, and 5/87 (5.7%) and 41/87 (47.1%) in shelter workers, respectively, with no statistical differences between groups. The high seroprevalence found herein indicates early environmental and urban spreading of SARS-CoV-2, associated with sociodemographic and economic vulnerability.

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