Author: Englmeier, L
Title: A theory on SARS-COV-2 susceptibility: reduced TLR7-activity as a mechanistic link between men, obese and elderly. Cord-id: r03gcno8 Document date: 2020_5_27
ID: r03gcno8
Snippet: Conti and Younes have pointed to a connection between lower TLR7 expression in men and their increased vulnerability towards a severe form of COVID-19 infection (1). I had started to investigate the same idea and think that I have discovered a wealth of additional supporting information that renders the hypothesis plausible and, if correct, could establish lower TLR7 activity/sensitivity as a common molecular characteristic of several high-risk patient groups.
Document: Conti and Younes have pointed to a connection between lower TLR7 expression in men and their increased vulnerability towards a severe form of COVID-19 infection (1). I had started to investigate the same idea and think that I have discovered a wealth of additional supporting information that renders the hypothesis plausible and, if correct, could establish lower TLR7 activity/sensitivity as a common molecular characteristic of several high-risk patient groups.
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