Author: Kulkarni, Hrishikesh S.; Atkinson, John P.
Title: Targeting complement activation in COVID-19 Cord-id: o2g7ixvy Document date: 2020_10_29
ID: o2g7ixvy
Snippet: In this issue of Blood, Yu et al have demonstrated that acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins activate complement by engaging the alternative pathway (AP) and that blocking this process by inhibiting factor D or C5 could mitigate SARS-CoV-2–induced immunopathology.(1)
Document: In this issue of Blood, Yu et al have demonstrated that acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins activate complement by engaging the alternative pathway (AP) and that blocking this process by inhibiting factor D or C5 could mitigate SARS-CoV-2–induced immunopathology.(1)
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