Selected article for: "antibody detection and early response"
Author: Ali, Ashaq; Rashid, Zubia; Zhou, Jieqiong; Zubair Yousaf, Muhammad; Galani, Saddia; Ashraf, Asma; Al-Ghanim, Khalid A.; Al-Suliman, Emin; Ahmed, Zubair; Farooq, Muhammad; Virik, Promy; Kaimkhani, Z.A.; Al-Mulhim, Norah; Mahboob, Shahid; Dong, Men; Huang, Qiuxiang
Title: Evaluating Antibody Response Pattern in Asymptomatic virus infected Pregnant females: Human Well-Being Study
  • Cord-id: r2k7kxyo
  • Document date: 2020_12_2
    • ID: r2k7kxyo
    Snippet: The ongoing SARS-CoV-2 pandemic infecting millions of people globally has given rise to serious public health threats. The need for early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic pregnant women is compelling to detect vertical transmission timely. Here, 11 SARS-CoV-2 asymptomatic pregnant cases from Wuhan China were investigated. All the patients were initially tested negative for SARS-CoV-2 on RT-PCR, so a chest CT scan was performed. Also, serum
    Document: The ongoing SARS-CoV-2 pandemic infecting millions of people globally has given rise to serious public health threats. The need for early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic pregnant women is compelling to detect vertical transmission timely. Here, 11 SARS-CoV-2 asymptomatic pregnant cases from Wuhan China were investigated. All the patients were initially tested negative for SARS-CoV-2 on RT-PCR, so a chest CT scan was performed. Also, serum antibody (IgM and IgG) titers were estimated. CT scan of patients revealed typical abnormalities related to SARS-CoV-2, indicating ground-glass opacity and infection lesions suggesting viral pneumonia. Elevated IgM and IgG antibodies levels (p<0.001) were also noticed in infected patients. Hence, CT imaging and serum antibody response are valuable in the early detection of SARS-CoV-2 in asymptomatic pregnant patients. These might serve as prognostic markers for healthcare professionals, in RT-PCR negative patients, to assess the effect of given treatment by chest CT.

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