Author: Arlin Stoltzfus; Ryan W. Norris
Title: On the causes of evolutionary transition:transversion bias Document date: 2015_9_28
ID: 4xocqn6o_7
Snippet: For the selective hypothesis, arguments to the effect that transitions are more conservative typically invoke a biochemical factor (or a composite such as the Grantham index) that correlates with patterns of evolutionary divergence, and is found to be more conserved by transitions than by transversions (e.g., Vogel and Kopun 1977; Zhang 2000) . This form of argument suffers from a logical circularity: if mutation shapes patterns of evolutionary a.....
Document: For the selective hypothesis, arguments to the effect that transitions are more conservative typically invoke a biochemical factor (or a composite such as the Grantham index) that correlates with patterns of evolutionary divergence, and is found to be more conserved by transitions than by transversions (e.g., Vogel and Kopun 1977; Zhang 2000) . This form of argument suffers from a logical circularity: if mutation shapes patterns of evolutionary amino acid replacement, then biochemical factors chosen for their ability to make sense of evolutionary patterns are not independent of mutation.
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